Title: Older people living with HIV and antiretroviral therapy: The prevalence of dysglycemia and risk factors

Abstract

Objective: To assess the prevalence and factors associated with dysglycemia (diabetes and prediabetes) in older people living with HIV infection. Method: This was a cross-sectional, analytical study with 59 older people living with HIV and using antiretroviral therapy, recruited by convenience sampling in two HIV referral hospitals in Recife (PE), between May/2018 and February/2020. The prevalence and factors associated with dysglycemia were analyzed by Chi-square, Fisher Exact, Kruskal-Wallis and Mann-Whitney tests. Results: The mean age of the 59 older peple 64.3 years and 66.1% were male. The prevalence of diabetes and prediabetes was 20.3% and 35.6%, respectively, and the significant risk factors were physical activity,coronary disease, riskof cardiovascular disease in ten years, HDL cholesterol levels and glycemia. Conclusion: A high prevalence of diabetes and prediabetes was observed in older people living with HIV. Interventions aimed at older people with HIV and the risk of diabetes and prediabetes are necessary, especially those with a sedentary life style, with a relevant cardiovascular risk and biochemical changes that participate in metabolic syndrome.