Title: Comparative study of response surface methodology and adaptive neuro-fuzzy inference system for removal of 6-APA in aqueous media

Abstract

Antibiotic contaminated waters treatment is an important step for pollutant reduction and the promotion of water environment quality. Uncertainty in wastewater treatment technology, fluctuations in effluent water quality and operation costs cause an emerging issue to develop materials effective for removal of antibiotics. The environment-friendly clay such as vermiculite, could be potentially promising candidates for removing 6-APA (6- Aminopenicillanic) from pharmaceutical effluent. Antibiotic removal was achieved by using eco-friendly, time-saving, powerful and easy-applying synthesis method via tetraethoxysilane (Si). Expert systems are widely powerful tools for minimizing the complexities and complications in wastewater treatment. Response surface methodology (RSM) and adaptive neuro-fuzzy inference system (ANFIS) models were used to develop systematically predicting interactions of synthesis conditions on 6-APA adsorption capacity and optimize the best amount of compound. The effect of process variables investigated by RSM through central composite design (CCD) matrix and the results compared with ANFIS model.

Biography

N. Soleimanpour Moghadam Ph.D. graduated from the Amirkabir University of Technology, Medicinal Mineral Chemistry branch as First-class with the highest distinction.She was awarded the 'Top student' in Ph.D. degree. She is also patented the invention of drug formulation in her own name in Iran. A major focus of her work was the study and development of polymers to deliver drugs, particularly antibiotics at controlled rates and for prolonged periods of time. Her research has been focused on the experimental design, synthesis, polymers, hydrogels, controlled release, characterization, XRD, XRF, SEM, FTIR, TEM, UV, BET analysis evaluation of novel biomaterials compounds, in Vitro assays, and in Vivo testing, and developing target-specific drug candidates as antibiotics.She also investigated the mechanism of release by using RSM, ANFIS techniques. She has published several authored articles and attended several conferences.

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